Anti-CD3 epsilon (activation epitope) APC
Product Specifications
CAS Number
9007-83-4
Gene Name
[CD3E]
NCBI Gene ID
916
Reactivity
Mouse, Human
Storage Conditions
Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.
Specificity
The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
Other Gene Names
[CD3E; CD3E; T3E; TCRE; IMD18; T3E]
Short Name
[CD3 epsilon]
Other Product Names
[T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3e molecule; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]
NCBI GI Number
1345708
NCBI Accession Number
P07766.2
Uniprot Accession Number
P07766
Available Sizes
Curated Selection
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