L-Aspartic aicd (disodium)

L-Aspartic acid disodium is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd disodium is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd disodium commonly used in the study of inflammatory conditions[1][2][3].

Product Specifications

CAS Number

[5598-53-8]

Product Name Alternative

Disodium L-aspartate

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-aspartic-aicd-disodium.html

Purity

97.0

Solubility

H2O : ≥ 50 mg/mL

Smiles

N[C@@H](CC(O[Na])=O)C(O[Na])=O

Molecular Formula

C4H5NNa2O4

Molecular Weight

177.07

Precautions

H302, H315, H319, H335

References & Citations

[1]Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73 (3) :1206-11.|[2]Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly (L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23 (4) :397-406.|[3]Su G, et al. Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. Redox Biol. 2024 May;71:103112.