Feruloylputrescine

Feruloylputrescine is an oral active phenolamide found in citrus plants and formed through the decarboxylation of L-Arginine. Feruloylputrescine inhibits monooxygenase (cntA) and reductase (cntB) and trimethylamine production. Feruloylputrescine can be used for cardiovascular diseases research[1].

Product Specifications

CAS Number

[501-13-3]

UNSPSC

12352005

Hazard Statement

H301+H311+H331, H315, H319, H335, H373

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/feruloylputrescine.html

Purity

99.34

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

COC1=C(O)C=CC(C=CC(NCCCCN)=O)=C1

Molecular Formula

C14H20N2O3

Molecular Weight

264.32

Precautions

H301+H311+H331, H315, H319, H335, H373

References & Citations

[1]Hana Lee, et al. Discovery of a Novel Bioactive Compound in Orange Peel Polar Fraction on the Inhibition of Trimethylamine and Trimethylamine N-Oxide through Metabolomics Approaches and In Vitro and In Vivo Assays: Feruloylputrescine Inhibits Trimethylamine via Suppressing cntA/B Enzyme. J Agric Food Chem. 2024 Apr 10;72 (14) :7870-7881. |[2]Nakase K, et al. Effects of pollen-extract components, diamines and derivatives of feruloylputrescine on isolated bladder and urethral smooth muscles of mice. Jpn J Pharmacol. 1990 Jun;53 (2) :157-64.