VUF 8430 (dihydrobromide)
VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].
Product Specifications
CAS Number
[100130-32-3]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vuf-8430-dihydrobromide.html
Purity
98.00
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
N=C(N)SCCNC(N)=N.[H]Br.[H]Br
Molecular Formula
C4H13Br2N5S
Molecular Weight
323.05
Precautions
H302, H315, H319, H335
References & Citations
[1]Lim HD, et al. Discovery of S- (2-guanidylethyl) -isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49 (23) :6650-1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H4 Receptor
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
HA710041 100 µg
Rabbit IgG (Fab Fragment specific), AlpHcAbs® Goat antibody (Biotin)
Ask
View Details 
MBS7273762-03 5x 96 Well
Rat Zinc finger CCCH domain containing protein 13 ELISA Kit
Ask
View Details 
MBS7273762-04 10x 96 Well
Rat Zinc finger CCCH domain containing protein 13 ELISA Kit
Ask
View Details