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VUF 8430 (dihydrobromide)

Product Specifications

UNSPSC Description

VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].

Target Antigen

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/vuf-8430-dihydrobromide.html

Purity

98.00

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

N=C(N)SCCNC(N)=N.[H]Br.[H]Br

Molecular Weight

323.05

References & Citations

[1]Lim HD, et al. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49(23):6650-1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-107555/VUF-8430-dihydrobromide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107555/VUF-8430-dihydrobromide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

100130-32-3

Available Sizes

Curated Selection

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