O4I2
O4I2 is a potent Oct3/4 inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1[1].
Product Specifications
CAS Number
[165682-93-9]
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Oct3/4
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/O4I2.html
Concentration
10mM
Purity
99.18
Solubility
DMSO : ≥ 42 mg/mL
Smiles
O=C(C1=CSC(NC2=CC=C(Cl)C=C2)=N1)OCC
Molecular Formula
C12H11ClN2O2S
Molecular Weight
282.75
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Cheng X, et al. Ethyl 2- ((4-Chlorophenyl) amino) thiazole-4-carboxylate and Derivatives Are Potent Inducers of Oct3/4. J Med Chem. 2015 Aug 13;58 (15) :5742-5750.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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