Benznidazole

Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease[1][2].

Product Specifications

CAS Number

[22994-85-0]

Product Name Alternative

Benznidazol; Ro 07-1051; Ro 71051

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Antibiotic; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/benznidazole.html

Purity

99.90

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NCC1=CC=CC=C1)CN2C=CN=C2[N+]([O-])=O

Molecular Formula

C12H12N4O3

Molecular Weight

260.25

Precautions

H315, H319, H335

References & Citations

[1]Bustamante JM, et al. Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy. Int J Antimicrob Agents. 2007 Jun;29 (6) :733-7.|[2]Luna KP, et al. In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica. 2009 Sep;29 (3) :448-55.