Benznidazole
Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease[1][2].
Product Specifications
CAS Number
[22994-85-0]
Product Name Alternative
Benznidazol; Ro 07-1051; Ro 71051
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Antibiotic; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/benznidazole.html
Purity
99.90
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=CC=C1)CN2C=CN=C2[N+]([O-])=O
Molecular Formula
C12H12N4O3
Molecular Weight
260.25
Precautions
H315, H319, H335
References & Citations
[1]Bustamante JM, et al. Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy. Int J Antimicrob Agents. 2007 Jun;29 (6) :733-7.|[2]Luna KP, et al. In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica. 2009 Sep;29 (3) :448-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Trypanosoma
Available Sizes
Curated Selection
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