Metaproterenol (hemisulfate)

Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2].

Product Specifications

CAS Number

[5874-97-5]

Product Name Alternative

Metaproterenol sulfate

UNSPSC

12352005

Hazard Statement

H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/metaproterenol-hemisulfate.html

Concentration

10mM

Purity

99.86

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=S(O)(O)=O.OC1=CC(O)=CC(C(O)CNC(C)C)=C1

Molecular Formula

C11H17NO3.1/2H2O4S

Molecular Weight

309.34

Precautions

H332

References & Citations

[1]Noh H, et al. Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications. Kidney Int. 2017 Jul;92 (1) :101-113.|[2]Ibrahim FA, et al. Highly sensitive spectrofluorimetric method for rapid determination of orciprenaline in biological fluids and pharmaceuticals. Luminescence. 2019 Feb;34 (1) :77-83.