17-HDHA
Product Specifications
UNSPSC Description
17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/17-hdha.html
Solubility
10 mM in DMSO
Smiles
CC/C=C\CC(O)/C=C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
Molecular Weight
344.49
References & Citations
[1]Ramon S, et al. The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant? J Immunol. 2014 Dec 15;193(12):6031-40.|[2]Ramon S, et al. Specialized proresolving mediators enhance human B cell differentiation to antibody-secreting cells. J Immunol. 2012 Jul 15;189(2):1036-42.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113512/17-HDHA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113512/
Clinical Information
No Development Reported
CAS Number
90780-52-2
Available Sizes
Curated Selection
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