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P005091

P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM.

Product Specifications

CAS Number

[882257-11-6]

Product Name Alternative

P5091

UNSPSC

12352005

Hazard Statement

H301, H413

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/P005091.html

Purity

99.92

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC(Cl)=C2Cl)S1)=O

Molecular Formula

C12H7Cl2NO3S2

Molecular Weight

348.22

Precautions

H301, H413

References & Citations

[1]Chauhan D, et al. A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell. 2012 Sep 11;22 (3) :345-58.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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