P005091
P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM.
Product Specifications
CAS Number
882257-11-6
Product Name Alternative
P5091
UNSPSC
12352005
Hazard Statement
H301, H413
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/P005091.html
Purity
99.92
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC(Cl)=C2Cl)S1)=O
Molecular Formula
C12H7Cl2NO3S2
Molecular Weight
348.22
Precautions
H301, H413
References & Citations
[1]Chauhan D, et al. A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Cancer Cell. 2012 Sep 11;22 (3) :345-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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