Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ABR-238901

ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4) . ABR-238901 has the potential for myocardial infarction (MI) research[1][2][3].

Product Specifications

CAS Number

1638200-22-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/abr-238901.html

Purity

98.92

Solubility

DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(NC1=C(O)C(Cl)=CN=C1)(C2=CN=C(C(Br)=C2)OC)=O

Molecular Formula

C11H9BrClN3O4S

Molecular Weight

394.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Kim De Veirman, et al. Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion. Cancer Immunol Res. 2017 Oct;5 (10) :839-846.|[2]Goran Marinković, et al. S100A9 Links Inflammation and Repair in Myocardial Infarction. Circ Res. 2020 Aug 14;127 (5) :664-676.|[3]A. Schiopu, et al. Short-term blockade of the S100A8/A9 alarmin in the immediate post-myocardial infarction period inhibits acute myocardial inflammation and preserves myocardial repair. European Heart Journal, Volume 38, Issue suppl_1, August 2017, ehx504.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

FAM100A (Family with Sequence Similarity 100, Member A, FLJ31223, FLJ32185, PP11303) (MaxLight 405) discontinued
245934-ML405 100 µL

FAM100A (Family with Sequence Similarity 100, Member A, FLJ31223, FLJ32185, PP11303) (MaxLight 405) discontinued

Sign In for Pricing
View Details
N-Boc-piperazine
TRC-B662000-1G 1 g

N-Boc-piperazine

Sign In for Pricing
View Details
POU2F1 Peptide - middle region
MBS3248570-01 0.1 mg

POU2F1 Peptide - middle region

Sign In for Pricing
View Details
POU2F1 Peptide - middle region
MBS3248570-02 5x 0.1 mg

POU2F1 Peptide - middle region

Sign In for Pricing
View Details
Interleukin 6 (IL6) Polyclonal Antibody
CAU28692-01 100 µL

Interleukin 6 (IL6) Polyclonal Antibody

Sign In for Pricing
View Details
Interleukin 6 (IL6) Polyclonal Antibody
CAU28692-02 200 µL

Interleukin 6 (IL6) Polyclonal Antibody

Sign In for Pricing
View Details