DNAJC2/MPP11 (phospho-Ser47) rabbit pAb
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
Gene ID
27000
UniProt
Q99543
Cellular Locus
Nucleus. Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Molecular Weight
68kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16926-1.pdf
Observed Molecular Weight
68 kD
Subcellular Location
Nucleus . Cytoplasm, cytosol .
Other Product Names
DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
Gene ID (Human)
27000
SwissProt (Human)
Q99543
Available Sizes
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