TLR9-IN-1
TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1].
Product Specifications
CAS Number
[2226366-86-3]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr9-in-1.html
Purity
99.67
Solubility
DMSO : 500 mg/mL (ultrasonic)
Smiles
O=C(C1CCN(CC1)C2=NN=CC3=CN(C4=CC=C(C)C=C4)N=C32)NCCCN(C)C
Molecular Formula
C23H31N7O
Molecular Weight
421.54
References & Citations
[1]Albert Frederick Candia, et al. Toll-like receptor antagonist compounds and methods of use. WO2018089695
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR9
Available Sizes
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