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BisSP1

BisSP1 is an antibody agent conjugates linker[1]. bisSP1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

2253947-15-6

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bissp1.html

Purity

95.39

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCCC(N[C@@H](CCCCN)C(NCCCN=[N+]=[N-])=O)=O

Molecular Formula

C12H23N9O2

Molecular Weight

325.37

References & Citations

[1]Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. Patent WO2018218004A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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