Biotin-PEG8-amine

Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTAC Linkers

Reference compound

PROTAC

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/biotin-peg8-amine.html

DMSO : ≥ 100 mg/mL

O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

638.81

[1]Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Room Temperature

http://file.medchemexpress.com/batch_PDF/HY-140899/Biotin-PEG8-amine-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-140899/Biotin-PEG8-amine-SDS-MedChemExpress.pdf

No Development Reported

2183447-27-8