SB-423562
SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist. SB-423562 has the potential for osteoporosis research.
Product Specifications
CAS Number
[351490-27-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
CaSR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/SB-423562.html
Purity
99.66
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
OC(CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC(C=CC=C3)=C3C2)=C1)=O
Molecular Formula
C26H32N2O4
Molecular Weight
436.54
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Kumar S, et al. An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation. Bone. 2010 Feb;46 (2) :534-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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