Human Claudin-4 Full Length Protein (VLP)
Human Claudin-4 Full Length Protein (VLP) (CL4-H52P5) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Val 209 (Accession # O14493-1) .
Product Specifications
Background
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Specifications
This protein .
Accession Number
O14493-1
Expression Region
Met 1 - Val 209
Host
HEK293
Target
Claudin-4
Conjugation
Unconjugated
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.
Endotoxin
1.0 EU per μg
Bioactivity
Immobilized Human Claudin-4 Full Length Protein (VLP) (Cat. No. CL4-H52P5) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human Claudin 4 antibody, Human IgG1 with a linear range of 1-63 ng/mL (QC tested).
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CL4-H52P5.pdf
Species
Human
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