IHVR-17028

IHVR-17028 is a potent and broad-spectrum antiviral agent. IHVR-17028 exhibits antiviral activity against BVDV, TCRV and DENV with EC50 values of 0.4 μM, 0.26 μM, 0.3 μM, respectively. IHVR-17028 is a potent ER α-glucosidase I inhibitor with an IC50 of 0.24 μM. IHVR-17028 can be used for infectious diseases research[1][2].

Product Specifications

CAS Number

[1428247-78-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ihvr-17028.html

Purity

99.61

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCCN(C(C(C)(C)C)=O)C2CCCCC2

Molecular Formula

C23H44N2O5

Molecular Weight

428.61

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jinhong Chang, et al. Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses.Antiviral Res. 2013 Jun;98 (3) :432-40.