Datopotamab
Product Specifications
UNSPSC Description
Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer[1].
Target Antigen
ADC Antibody; TROP2
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related;Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/datopotamab.html
Purity
99.00
Solubility
10 mM in DMSO
Smiles
[Datopotamab]
References & Citations
[1]Okajima D, et al. Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells. Mol Cancer Ther. 2021 Dec;20(12):2329-2340.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99843/Datopotamab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99843/Datopotamab-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
2267989-53-5
Available Sizes
Curated Selection
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