AChE/BChE-IN-11
AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].
Product Specifications
CAS Number
80443-12-5
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-11.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(O)=C2C(O[C@H](C3=CC(O)=C(O)C(O)=C3)[C@@H](O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C2=O)=C1
Molecular Formula
C21H22O12
Molecular Weight
466.39
References & Citations
[1]Elsebai MF, et, al. X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside. Sci Rep. 2022 Nov 1;12 (1) :18351.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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