AChE/BChE-IN-11

AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].

Product Specifications

CAS Number

[80443-12-5]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-bche-in-11.html

Solubility

10 mM in DMSO

Smiles

OC1=CC(O)=C2C(O[C@H](C3=CC(O)=C(O)C(O)=C3)[C@@H](O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C2=O)=C1

Molecular Formula

C21H22O12

Molecular Weight

466.39

References & Citations

[1]Elsebai MF, et, al. X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside. Sci Rep. 2022 Nov 1;12 (1) :18351.