Lys-Gln-Ala-Gly-Asp-Val

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) [1][2].

Product Specifications

CAS Number

[80755-87-9]

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

COVID-19-anti-virus

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lys-gln-ala-gly-asp-val.html

Purity

99.75

Solubility

H2O : ≥ 100 mg/mL

Smiles

CC(C)[C@@H](C(O)=O)NC([C@H](CC(O)=O)NC(CNC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O

Molecular Formula

C25H44N8O10

Molecular Weight

616.66

References & Citations

[1]Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33 (9) :2593-9. |[2]Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22 (5) :439-44.