MAC glucuronide linker-2
MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[229977-57-5]
UNSPSC
12352203
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mac-glucuronide-linker-2.html
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(CO)C=C2N
Molecular Formula
C20H25NO11
Molecular Weight
455.41
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Robert A, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Glycosidase Cleavable Linker
Available Sizes
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