XMU-MP-1
XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively[1].
Product Specifications
CAS Number
[2061980-01-4]
UNSPSC
12352005
Hazard Statement
H302
Target
Hippo (MST)
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/XMU-MP-1.html
Purity
99.93
Solubility
DMSO : 8 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(NC2=NC=C(C(N(C)C3=C4SC=C3)=N2)N(C)C4=O)C=C1)(N)=O
Molecular Formula
C17H16N6O3S2
Molecular Weight
416.48
Precautions
H302
References & Citations
[1]Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med. 2016 Aug 17;8 (352) :352ra108.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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