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DDR1/2 inhibitor-2

Product Specifications

UNSPSC Description

DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases[1].

Target Antigen

Discoidin Domain Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ddr1-2-inhibitor-2.html

Solubility

DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5

Molecular Weight

492.45

References & Citations

[1]Inder Bhamra, et al. Phenyl- and pyridopyrazole derivatives as inhibitors of ddr1. Patent. WO2023021278.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156552/DDR1-2-inhibitor-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156552/DDR1-2-inhibitor-2-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2908756-11-4

Available Sizes

Curated Selection

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