DDR1/2 inhibitor-2
Product Specifications
UNSPSC Description
DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases[1].
Target Antigen
Discoidin Domain Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ddr1-2-inhibitor-2.html
Solubility
DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5
Molecular Weight
492.45
References & Citations
[1]Inder Bhamra, et al. Phenyl- and pyridopyrazole derivatives as inhibitors of ddr1. Patent. WO2023021278.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156552/DDR1-2-inhibitor-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156552/DDR1-2-inhibitor-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2908756-11-4
Available Sizes
Curated Selection
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