Propranolol (hydrochloride)
Propranolol hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively[1]. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM[2]. Propranolol hydrochloride is used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[3].
Product Specifications
CAS Number
[318-98-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Propranolol-hydrochloride.html
Purity
99.97
Solubility
DMSO : ≥ 150 mg/mL|H2O : 33.33 mg/mL (ultrasonic)
Smiles
OC(CNC(C)C)COC1=CC=CC2=CC=CC=C12.Cl
Molecular Formula
C16H22ClNO2
Molecular Weight
295.80
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
β adrenergic receptor
Citation 01
Available Sizes
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