FABP4-IN-4
Product Specifications
UNSPSC Description
FABP4-IN-4 (Compound 30) is an orally active inhibitor for FABP, with IC50 of 1.18 μM for FABP 1. FABP4-IN-4 improves the glucose tolerance, reduces the level of blood glucose, plasma lipids and hepatic inflammatory factors, attenuates hepatic steatosis, and exhibits anti-inflammatory effects in mouse diet-induced obesity models[1].
Target Antigen
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fabp4-in-4.html
Smiles
O=S(C1=C(N=CC=C2)C2=CC=C1)(N3CCN(S(C4=C(C5=CC=CC(O)=C5)C=CC=C4)(=O)=O)CC3)=O
Molecular Weight
509.60
References & Citations
[1]Chen L, et al., Design, synthesis, and biological evaluation of novel highly selective non-carboxylic acid FABP1 inhibitors. Eur J Med Chem. 2024 Jul 22;276:116705.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161892/FABP4-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161892/
Clinical Information
No Development Reported
Curated Selection
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