L-770644 (dihydrochloride)
Product Specifications
UNSPSC Description
L-770644 is an orally active, potent and selective agonist of the human β3 adrenergic receptor (EC50 = 13 nM)[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-770644-dihydrochloride.html
Smiles
O=C1N(C2=CC=C(C=C2)S(NC3=CC=C(C=C3)CCNC[C@@H](C4=CN=CC=C4)O)(=O)=O)N=NN1CCCC5CCCC5.Cl.Cl
Molecular Weight
664.65
References & Citations
[1]Shih TL, et al. L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability. Bioorg Med Chem Lett. 1999 May 3;9(9):1251-4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124208A/L-770644-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124208A/
Clinical Information
Phase 1
CAS Number
182251-68-9
Curated Selection
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