Vitexilactone

Vitexilactone is a diterpenoid that can be isolated from the leaves of Vitex negundo L. Vitexilactone shows antimicrobial activity towards E. coli. Vitexilactone induces cell apoptosis and inhibits cell cycle of cancer cells. Vitexilactone can be used for the research of cancer[1][2].

Product Specifications

CAS Number

[61263-49-8]

UNSPSC

12352005

Target

Apoptosis; Bacterial

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/vitexilactone.html

Purity

97.47

Solubility

10 mM in DMSO

Smiles

O=C1OCC(CC[C@@]2(O)[C@H](C)C[C@@H](OC(C)=O)[C@@]3([H])C(C)(C)CCC[C@]23C)=C1

Molecular Formula

C22H34O5

Molecular Weight

378.50

References & Citations

[1]Sichaem J, et al. A new labdane-type diterpenoid from the leaves of Vitex negundo L. Nat Prod Res. 2021 Jul;35 (14) :2329-2334.|[2]Li WX, et al. Labdane-type diterpenes as new cell cycle inhibitors and apoptosis inducers from Vitex trifolia L. J Asian Nat Prod Res. 2005 Apr;7 (2) :95-105.