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DPP-IV-IN-2

DPP-IV-IN-2 is an inhibitor of both dipeptidyl peptidase IV (DPIV) and DP8/9 with IC50s of 0.1 and 0.95 μM, respectively.

Product Specifications

CAS Number

[136259-18-2]

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/H-Lys_4-nitro-Z_-pyrrolidide.html

Purity

99.35

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OCC1=CC=C([N+]([O-])=O)C=C1)NCCCC[C@H](N)C(N2CCCC2)=O

Molecular Formula

C18H26N4O5

Molecular Weight

378.42

References & Citations

[1]Ansorge S, et al. Novel aspects of cellular action of dipeptidyl peptidase IV/CD26. Biol Chem. 2011 Mar;392 (3) :153-68.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DPP-4

Available Sizes

Curated Selection

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