Carbazomycin D
Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively[1].
Product Specifications
CAS Number
[108073-63-8]
UNSPSC
12352005
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/carbazomycin-d.html
Smiles
COC(C(C1=C2)=C3NC1=CC=C2OC)=C(C(C)=C3C)OC
Molecular Formula
C17H19NO3
Molecular Weight
285.34
References & Citations
[1]Intaraudom C, et al. Antimalarial and antituberculosis substances from Streptomyces sp. BCC26924[J]. Tetrahedron, 2011, 67 (39) : 7593-7597.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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