KR-31080
KR-31080 is an derivative of imidazo [4,5-b] pyridine. KR-31080 inhibits angiotensin II receptor. KR-31080 inhibits the NO production in LPS-stimulated BV-2 cells at a concentration of 2 μm with inhibition of 8.3%[1].
Product Specifications
CAS Number
[174800-22-7]
Product Name Alternative
SK-1080
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kr-31080.html
Smiles
O=N1=C(C2=CC3=C(N=C2C)N(CC4=CC=C(C5=C(C6=NN=NN6)C=CC=C5)C=C4)C(CCCC)=N3)C=CC=C1
Molecular Formula
C30H28N8O
Molecular Weight
516.60
References & Citations
[1]Jiyeon Ock, et al. A novel anti-neuroinflammatory pyridylimidazole compound KR-31360. Biochem Pharmacol. 2010 Feb 15;79 (4) :596-609.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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