GSK334429
GSK334429 is a selective and orally active non-imidazole histamine H3 receptor antagonist with a pKi of 9.49 against human H3 receptor. GSK334429 can be utilized in neurological research[1].
Product Specifications
CAS Number
[799557-57-6]
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk334429.html
Smiles
O=C(N1CCN(C(C)C)CCC1)C2CCN(C3=CC=C(C(F)(F)F)N=C3)CC2
Molecular Formula
C20H29F3N4O
Molecular Weight
398.47
References & Citations
[1]Medhurst AD, et al. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats. Biochem Pharmacol. 2007 Apr 15;73 (8) :1182-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9306829-01 48 Well
Human Rho Guanine Nucleotide Exchange Factor 3 (ARHGEF3) ELISA Kit
Ask
View Details MBS9306829-02 96 Well
Human Rho Guanine Nucleotide Exchange Factor 3 (ARHGEF3) ELISA Kit
Ask
View Details MBS9306829-03 5x 96 Well
Human Rho Guanine Nucleotide Exchange Factor 3 (ARHGEF3) ELISA Kit
Ask
View Details MBS9306829-04 10x 96 Well
Human Rho Guanine Nucleotide Exchange Factor 3 (ARHGEF3) ELISA Kit
Ask
View Details 
MBS6188410-01 0.1 mL
PACAP Type I Receptor (Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor, PACAP-R-1, PACAP-R1, ADCYAP1R1) (MaxLight 405)
Ask
View Details 
MBS6188410-02 5x 0.1 mL
PACAP Type I Receptor (Pituitary Adenylate Cyclase-activating Polypeptide Type I Receptor, PACAP-R-1, PACAP-R1, ADCYAP1R1) (MaxLight 405)
Ask
View Details