SHB Recombinant Rabbit Monoclonal Antibody [JE57-12]
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Product Specifications
Product Name Alternative
Abbreviation
SHB
Swiss Prot
Q15464 Human
Cellular Locus
Cytoplasm, Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human SHB aa 450-509.
Isotype
IgG
Clone
JE57-12
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, K-562 cell lysate, HEK-293 cell lysate, A549.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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