SHB Recombinant Rabbit Monoclonal Antibody [JE57-12]
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SHB
Swiss Prot
Q15464 Human
Cellular Locus
Cytoplasm, Cell membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human SHB aa 450-509.
Isotype
IgG
Clone
JE57-12
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, K-562 cell lysate, HEK-293 cell lysate, A549.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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