SHB Recombinant Rabbit Monoclonal Antibody [JE57-12]

Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

bA3J10.2 antibody OTTHUMP00000021397 antibody RP11 3J10.8 antibody RP113J10.8 antibody SH2 domain containing adapter protein B antibody SH2 domain-containing adapter protein B antibody SHB (Src homology 2 domain containing) adaptor protein B antibody SHB adaptor protein (a Src homology 2 protein) antibody SHB adaptor protein antibody Shb antibody SHB_HUMAN antibody Src homology 2 domain containing adaptor protein B antibody Src homology 2 protein antibody

Abbreviation

SHB

Swiss Prot

Q15464 Human

Cellular Locus

Cytoplasm, Cell membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human SHB aa 450-509.

Isotype

IgG

Clone

JE57-12

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC

Positive Control

HeLa cell lysate, HepG2 cell lysate, MCF7 cell lysate, K-562 cell lysate, HEK-293 cell lysate, A549.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 55 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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