MMP-7-IN-3
MMP-7-IN-3 is a potent and selective inhibitor of MMP-7. MMP-7-IN-3 suppresses kidney fibrosis progression in a mouse model with unilateral ureteral obstruction[1].
Product Specifications
CAS Number
2865097-58-9
UNSPSC
12352209
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-7-in-3.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(N[C@H](C(O)=O)CCC(NCC(N[C@@H](CC1=CC=NC=C1)C(N[C@@H](C(C)(C)C)C(N2[C@@H](CCC2)CC(N)=O)=O)=O)=O)=O)(C3=CC(C(F)(F)F)=C(C=C3)Cl)=O
Molecular Formula
C34H43ClF3N7O9S
Molecular Weight
818.26
References & Citations
[1]Abe-Sato K, et al. Structure-Based Optimization and Biological Evaluation of Potent and Selective MMP-7 Inhibitors for Kidney Fibrosis. J Med Chem. 2023 Oct 20.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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