18-Azido-stearic acid
Product Specifications
UNSPSC Description
18-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Target Antigen
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/18-azido-stearic-acid.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCCCCCCCCCCCCCCCCN=[N+]=[N-]
Molecular Weight
325.49
References & Citations
[1]Ejendal KFK, et al. Protein Labeling and Bioconjugation Using N-Myristoyltransferase. Methods Mol Biol. 2019;2033:149-165.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151692/18-Azido-stearic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151692/18-Azido-stearic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1529763-58-3
Available Sizes
Curated Selection
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