Fostemsavir Tris

Fostemsavir Tris (BMS-663068 (Tris) ) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris) ) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.

Product Specifications

CAS Number

[864953-39-9]

Product Name Alternative

BMS-663068 (Tris)

UNSPSC

12352005

Hazard Statement

H317, H360, H373

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/BMS-663068-Tris.html

Purity

99.78

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(C(C2=CC=CC=C2)=O)CC1)C(C3=CN(COP(O)(O)=O)C4=C3C(OC)=CN=C4N5N=C(C)N=C5)=O.OCC(CO)(N)CO

Molecular Formula

C29H37N8O11P

Molecular Weight

704.62

Precautions

H317, H360, H373

References & Citations

[1]Nowicka-Sans B, et al. In vitro antiviral characteristics of HIV-1 attachment inhibitor BMS-626529, the active component of the prodrug BMS-663068. Antimicrob Agents Chemother. 2012 Jul;56 (7) :3498-507.