(3S,5S) -Pitavastatin (calcium)

(3S,5S) -Pitavastatin calcium is the 3-epimer of Pitavastatin Calcium (HY-B0144) . Pitavastatin Calcium is a potent HMG-CoA reductase inhibitor that can be used for the study of cardiovascular disease[1].

Product Specifications

CAS Number

[254452-92-1]

UNSPSC

12352005

Hazard Statement

H302, H361, H362

Target

HMG-CoA Reductase (HMGCR)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3s-5s-pitavastatin-hemicacium.html

Purity

99.94

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

[O-]C(C[C@@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=C(C=CC=C3)N=C1C4CC4)=O.[1/2].[Ca+2]

Molecular Formula

C25H24FNO4.1/2Ca

Molecular Weight

440.49

Precautions

H302, H361, H362

References & Citations

[1]Suzuki M, et al. First systematic chiral syntheses of two pairs of enantiomers with 3,5-dihydroxyheptenoic acid chain, associated with a potent synthetic statin NK-104. Bioorg Med Chem Lett. 1999 Oct 18;9 (20) :2977-82.