BF738735
BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM.
Product Specifications
CAS Number
1436383-95-7
UNSPSC
12352005
Target
PI4K; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection; PI3K/Akt/mTOR
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/PI4KIII_beta_-IN-1.html
Concentration
10mM
Purity
99.26
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C2=C(C)N=C3C(NCC4=CC=CC(S(=O)(C)=O)=C4)=NC=CN32)C=C1F
Molecular Formula
C21H19FN4O3S
Molecular Weight
426.46
References & Citations
[1]van der Schaar HM, et al. A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ. Antimicrob Agents Chemother. 2013 Oct;57 (10) :4971-81.|[2]V Saarnio. Antiviral Molecules of Enteroviruses. 13.1.2017.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI4KIIIα; PI4KIIIβ
Available Sizes
Frequently Asked Questions
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