BF738735

BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM.

Product Specifications

CAS Number

[1436383-95-7]

UNSPSC

12352005

Target

PI4K; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection; PI3K/Akt/mTOR

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/PI4KIII_beta_-IN-1.html

Concentration

10mM

Purity

99.26

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C2=C(C)N=C3C(NCC4=CC=CC(S(=O)(C)=O)=C4)=NC=CN32)C=C1F

Molecular Formula

C21H19FN4O3S

Molecular Weight

426.46

References & Citations

[1]van der Schaar HM, et al. A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ. Antimicrob Agents Chemother. 2013 Oct;57 (10) :4971-81.|[2]V Saarnio. Antiviral Molecules of Enteroviruses. 13.1.2017.