Infigratinib phosphate
Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the FGFR family with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
Product Specifications
CAS Number
[1310746-10-1]
Product Name Alternative
BGJ-398 phosphate; NVP-BGJ398 (phosphate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NVP-BGJ398-phosphate.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : 8.75 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=P(O)(O)O.ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O
Molecular Formula
C26H34Cl2N7O7P
Molecular Weight
658.47
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Available Sizes
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