What is the catalog number for Infigratinib phosphate?

The catalog number for Infigratinib phosphate is HY-13311A.

What sizes are available for Infigratinib phosphate?

Infigratinib phosphate is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 50 mg, 100 mg.

How many pack sizes does Infigratinib phosphate come in?

Infigratinib phosphate is available in 5 different pack sizes.

Is Infigratinib phosphate in stock?

Infigratinib phosphate is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Infigratinib phosphate?

Infigratinib phosphate is manufactured by QuantiMol.

What is the estimated delivery time for Infigratinib phosphate?

Estimated delivery time for Infigratinib phosphate is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Infigratinib phosphate?

The safety data sheet for Infigratinib phosphate is available here: http://file.medchemexpress.com/batch_PDF/HY-13311A/Infigratinib-phosphate-SDS-MedChemExpress.pdf.

Infigratinib phosphate

Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the FGFR family with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

Product Specifications

CAS Number

1310746-10-1

Product Name Alternative

BGJ-398 phosphate; NVP-BGJ398 (phosphate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/NVP-BGJ398-phosphate.html

Concentration

10mM

Purity

99.59

Solubility

DMSO : 8.75 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(O)(O)O.ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O

Molecular Formula

C26H34Cl2N7O7P

Molecular Weight

658.47

Precautions

H302, H315, H319

References & Citations

[1]Guagnano V, et al. Discovery of 3- (2,6-Dichloro-3,5-dimethoxy-phenyl) -1-{6-[4- (4-ethyl-piperazin-1-yl) -phenylamino]-pyrimidin-4-yl}-1-me thyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor T|[2]Konecny GE, et al. Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells. Mol Cancer Ther. 2013 May;12 (5) :632-42.