20-HC-Me-Pyrrolidine
20-HC-Me-Pyrrolidine is a potent Aster protein inhibitor with IC50s of 0.11 μM, 0.06 μM, and 0.71 μM for Aster-A, Aster-B, and Aster-C, respectively. 20-HC-Me-Pyrrolidine blocks the ability of Asters to bind and transfer cholesterol. 20-HC-Me-Pyrrolidine also inhibits the movement of low-density lipoprotein (LDL) cholesterol to the endoplasmic reticulum (ER) [1].
Product Specifications
UNSPSC
12352005
Target
CETP; LDLR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/20-hc-me-pyrrolidine.html
Purity
99.69
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OCCN5CCCC5)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(O)(C)C
Molecular Formula
C28H47NO2
Molecular Weight
429.68
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD50 (ICAM-3) (101-1D2), CF594 conjugate, 0.1mg/mL
CD63 (MX-49.129.5), CF640R conjugate, 0.1mg/mL
CD50 / ICAM3 (CG106), CF594 conjugate, 0.1mg/mL
