Bispyribac (sodium)

Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic[1][2][3][4].

Product Specifications

CAS Number

[125401-92-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Acetolactate Synthase (ALS) ; SOD

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/bispyribac-sodium.html

Purity

99.56

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(O[Na])C1=C(OC2=NC(OC)=CC(OC)=N2)C=CC=C1OC3=NC(OC)=CC(OC)=N3

Molecular Formula

C19H17N4NaO8

Molecular Weight

452.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Ahmad F, Anwar S, Firdous S, Da-Chuan Y, Iqbal S. Biodegradation of bispyribac sodium by a novel bacterial consortium BDAM: Optimization of degradation conditions using response surface methodology. J Hazard Mater. 2018;349:272-281.|[2]Osuna M D, et al. Cross-resistance to bispyribac-sodium and bensulfuron-methyl in Echinochloa phyllopogon and Cyperus difformis. Pesticide Biochemistry and Physiology, 2002, 73 (1) : 9-17.|[3]Sleem R F, et al. Genotoxicity of bispyribac sodium in albino rats. Mansoura Veterinary Medical Journal, 2017, 18 (1) : 491-502.|[4]Nasir A S, et al. Bispyribac Sodium Induced Oxidative Stress and Hepatotoxicity in the Female Rats. Annals of the Romanian Society for Cell Biology, 2021, 25 (7) : 273-283.