Asp-AMS
Asp-AMS, an analogue of aspartyl-adenylate, is an aspartyl-tRNA synthetase inhibitor and also a strong competitive inhibitor of the mitochondrial enzyme.
Product Specifications
CAS Number
[828288-98-8]
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase; Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Asp-AMS.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C2N=CN([C@@H]([C@H](O)[C@@H]3O)O[C@@H]3COS(=O)(NC([C@@H](N)CC(O)=O)=O)=O)C2=NC=N1
Molecular Formula
C14H19N7O9S
Molecular Weight
461.41
References & Citations
[1]Messmer M, et al. Peculiar inhibition of human mitochondrial aspartyl-tRNA synthetase by adenylate analogs. Biochimie. 2009 May;91 (5) :596-603.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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