NOTA-NHS ester

NOTA-NHS ester is a molecule related to radiolabeling drugs (RDC) that can be used for fluorescent labeling and radioactive nuclide labeling applications[1][2].

Product Specifications

CAS Number

[1338231-09-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Radionuclide-Drug Conjugates (RDCs)

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nota-nhs-ester.html

Purity

97.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(O)CN1CCN(CC(ON2C(CCC2=O)=O)=O)CCN(CC(O)=O)CC1

Molecular Formula

C16H24N4O8

Molecular Weight

400.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Lang L, et al. Stability analysis of glutamic acid linked peptides coupled to NOTA through different chemical linkages. Mol Pharm. 2014 Nov 3;11 (11) :3867-74.|[2]Chen CJ, et al. 68Ga-labelled NOTA-RGD-GE11 peptide for dual integrin and EGFR-targeted tumour imaging. Nucl Med Biol. 2019 Jan-Feb;68-69:22-30.