Gondoic acid

Gondoic acid (cis-11-Eicosenoic acid), a monounsaturated long-chain fatty acid, is contained in a variety of plant oils and nuts. Gondoic acid can exert anti-inflammatory activity by inhibiting the production of ROS and the PKCθ/ERK/STAT3 signaling pathway. Gondoic acid can be used as a raw material for medical supplies and a moisturizing ingredient in cosmetic creams[1][2].

Product Specifications

CAS Number

[5561-99-9]

Product Name Alternative

Cis-11-Eicosenoic acid

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; ERK; PKC; Reactive Oxygen Species (ROS) ; STAT

Type

Natural Products

Related Pathways

Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt; TGF-beta/Smad

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/gondoic-acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCC/C=C\CCCCCCCCCC(O)=O

Molecular Formula

C20H38O2

Molecular Weight

310.51

Precautions

H302, H315, H319, H335

References & Citations

[1]H Kikukawa, et al. Production of cis-11-eicosenoic acid by Mortierella fungi. J Appl Microbiol. 2015 Mar;118 (3) :641-7.|[2]Fan G, et al. Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway. Int Immunopharmacol. 2022 Oct;111:109171.